HIV TREATMENT: MONOTHERAPY
Friday, March 27th, 2009In general, treatment with only one of the agents [monotherapy] has been found to be inferior to treatment with two or more of the drugs [combination therapy). Most providers have now abandoned monotherapy because the data so clearly demonstrate that combination therapy works significantly better. However, combination therapy raises the possibility of more potential side effects and involves greater cost. Thus, once again, any treatment plan must be individualized.
The goal of treatment is to decrease the viral load to undetectable levels. If the viral load is greater than 30,000 to 50,000, then medication should be considered even if the T-helper-cell count is stable and a person is feeling well physically. If the T-helper-cell count is decreasing, or a person is experiencing progression of the infection with various opportunistic infections, then medications should be considered even if the viral load is low and stable.
*330\213\8*